Yastimadhu (licorice) is helpful for many respiratory disorders as well as cough. Yastimadhu or licorice helps to increase the appetite by assisting proper evacuation of stools. This herb has a special action on kapha humor that helps in expectoration of the accumulated kapha. It is primarily used as an expectorant and anti-tussive agent. It has shown anti-inflammatory activity. The glycorrhiza or licorice extract is now are significant substance for treatment of gastric and duodenal ulcers. A burly decoction makes an efficient laxative for children and may also help to reduce fever. Add licorice or yastimadhu to other medicines to make them more pleasant.

The root is tonic, cooling, demulcent, expectorant, and diuretic, emmenagogue and gentle laxative. The principal constituent of licorice is glycyrrhizin (also known as glycyrrhizic acid), which is efficient in the treatment of chronic hepatitis and liver cirrhosis. Glyrrhizin inhibits liver cell injury but does not reverse reduced protein synthesis. Licorice is also used for the treatment of asthma, acute and chronic bronchitis, chronic cough, hoarseness, sore throat and to release phlegm and reduce fever. Glycyrrhizin stimulates the secretion of the adrenal cortex hormone “aldosterone”. This herb can be as efficient as codeine, and safer, when used as a cough suppressant. It alleviates irritable conditions of the mucus membrane, strengthens immune system and provides confrontation in recurring infections.

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Yastimadhu (Licorice) Herbal Dietary Supplement: 60 Vegetable Capsules

Packs Retail Price Sale Price Shipping Order Now 2 Bottle $35.00 $35.00 Free 3 Bottle $53.00 $47.00 Free 5 Bottles $88.00 $69.00 Free 10 Bottles $175.00 $129.00 Free

Serving size: 2 Vegi caps
Servings per container: 30
Each 500 mg capsule contains: Yastimadhu

Dosage: 1-2 Capsules two times a day after meal or or as directed by your health practitioner.

It tones up the bowels and is a mild anti-inflammatory for arthritis and is used to treat viral liver inflammation, gastric, duodenal and esophageal ulceration or inflammation, heartburn and mouth ulcers. It stimulates production of hormones by the adrenal glands and reduces the breakdown of steroids by the liver and kidneys. It induces menstrual flow and expels the placenta after child-birth. Licorice is a very powerful anti-depressant. At least 8 licorice compounds are monoamine oxidase (MAO) inhibitors. (MAO inhibitors are compounds are capable of effective anti-depressant action.)

1. Yastimadhu (licorice) can be chewed on to relieve sore throats.
2. It is also beneficial in gastro intestinal ulcers.
3. Gargling with an infusion of Licorice or yastimadhu root is reputed to relieve oral inflammations, dry coughs, bronchitis and asthma.
4. Soothes irritation caused by acids, and coats digestive and urinary tracts. Hence, Licorice may be prescribed for dyspepsia, heartburn, and gastric ulcers.
5. Due to its anti-inflammatory actions, yastimadhu is a time-honored remedy for arthritis.
6. Superficially applied for treating conditions like eczema, herpes, and canker sores (mouth ulcers).
7. Yastimadhu strengthens the immune system.
8. At present, the herb is being investigated as a possible cancer treatment. It is suspected that the compounds in Licorice root may be able to inhibit the growth of cancerous cells.
9. Other usefulness of yastimadhu is Amenorrhea, Anemia, Arthritis, Asthma, Bronchitis, Catarrh, Cirrhosis, Common Cold, Cough, Depression, Fatigue, Fevers, Flatulence, Flu, Gastritis, Heartburn, Hepatitis, High LDL Cholesterol Level, Indigestion, Irritable Bowel Syndrome (IBS), Lack of Appetite, Laryngitis, Liver Dysfunction, and Persistent Infection due to Low Immunity, Phlegmatic Cough, Sore Throat, Tuberculosis, Ulcers, Under-developed Breasts, and Urinary Tract Infection (UTI).

In-vitro and in-vivo neuroprotective effect and mechanisms of glabridin, a major active iso-flavan from Glycyrrhiza glabra (yastimadhu). By Yu XQ, Xue CC, Zhou ZW, Li CG, Du YM, Liang J, Zhou SF.

The research was carried out at Department of Nephrology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. Stroke is a life-threatening illness distinguished by quickly developing clinical signs of focal or global commotion of cerebral function due to cerebral ischemia. A number of flavonoids have been shown to assuage the cerebral injuries in stroked animal models. Glabridin, a major flavonoid of Glycyrrhiza glabra (yastimadhu), possesses multiple pharmacological activities. This study aimed to examine whether glabridin modulated the cerebral injuries induced by middle cerebral artery occlusion (MCAO) in rats and staurosporine-induced damage in cultured rat cortical neurons and the probable mechanisms involved. Our study showed that glabridin at 25mg/kg by intra-peritoneal injection, but not at 5 mg/kg, considerably reduced the focal infarct volume, cerebral histological damage and apoptosis in middle cerebral artery occlusion or MCAO rats compared to sham-operated rats. Glabridin considerably attenuated the level of brain malonyldialdehyde (MDA) in middle cerebral artery occlusion or MCAO rats, while it elevated the level of two endogenous antioxidants in the brain, i.e. superoxide dismutase (SOD) and reduced glutathione (GSH). Co-treatment with glabridin considerably inhibited the staurosporine-induced cytotoxicity and apoptosis of cultured rat cortical neurons in a concentration-dependent manner. Constantly, glabridin appreciably reduced the DNA laddering caused by staurosporine in a concentration-dependent manner. Glabridin also concealed the elevated Bax protein and caspase-3 proenzyme and decreased bcl-2 induced by staurosporine in cultured rat cortical neurons, assisting cell survival. Glabridin also inhibited superoxide production in cultured cortical neurons uncovered to staurosporine. These findings indicated that glabridin had a neuroprotective result via modulation of multiple pathways linked with apoptosis. Further studies are necessary to further investigate the biochemical mechanisms for the protective effect of glabridin on neurons and the evidence for clinical use of yastimadhu in the management of cerebral ischemia.